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For those who survive, as many as 19% suffer serious long-term consequences such as deafness, neurological damage or limb loss. Available at: http://www.05) survival advantage, statistically significant differences in body weights and wet lung weights were seen over the first six weeks of the study. AEOL 10150 also demonstrated statistically significant reductions in markers for oxidative stress and inflammation – secondary endpoints for the study. “We believe AEOL 10150 could be a compelling countermeasure for Acute Radiation Syndrome (“ARS”) and are committed to working with our partners at Duke University, the University of Maryland and the National Institutes of Health (NIH) National Institutes of Allergies and Infectious Diseases (NIAID) to accelerate the development and approval of this product with the goal of providing protection against nuclear and radiological threats to the citizens of our country. Additionally, based on its mechanism, it is believed that the compound may potentially protect against exposure to chlorine gas. AEOL 10150 is a patented, small molecule catalytic antioxidant that mimics and thereby amplifies the body's natural enzymatic systems for eliminating reactive oxygen species, or free radicals.
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--(BUSINESS WIRE)--Jul 6, 2009 - Aeolus Pharmaceuticals, Inc. While Asia has primarily seen serogroup A, recent outbreaks of serogroup C have been noted.
About Aeolus Pharmaceuticals
Aeolus is developing a variety of therapeutic agents based on its proprietary small molecule catalytic antioxidants, with AEOL 10150 being the first to enter human clinical evaluation.
Potential for AEOL 10150 as a Countermeasure Against Multiple Terrorist Threats
AEOL 10150 has shown significant protective effects against radiation and mustard gas in animal models. Should one or more of these risks or uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those anticipated, believed, estimated or expected. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof.
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