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About meningococcal disease
Meningococcal disease can manifest as bacterial meningitis - an infection of the protective coverings of the brain and spinal cord - or meningococcemia - a bloodstream infection[2].
Five serogroups cause the majority of meningococcal disease worldwide: A, B, C, W-135 and Y[1].
About Novartis
Novartis Vaccines and Diagnostics is a division of Novartis focused on the development of preventive treatments. Approximately USD 7. For more information, please visit www.] Snape, MD et al.--(BUSINESS WIRE)--Jul 6, 2009 - Aeolus Pharmaceuticals, Inc.
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About the Novartis Vaccines global meningococcal franchise
Menveo is based on the same proprietary technology Novartis Vaccines pioneered to produce Menjugate, a meningococcal serogroup C conjugate vaccine approved outside the US since 2000 for use in individuals from age 2 months through adulthood. Immune memory typically takes up to five days to develop, so there often is not enough time for immune memory to mount a protective response[3]. Focused solely on healthcare, Novartis offers a diversified portfolio to best meet these needs: innovative medicines, cost-saving generic pharmaceuticals, preventive vaccines, diagnostic tools and consumer health products.novartis. Prevention and Control of Meningococcal Disease - Recommendations of the Advisory Committee on Immunization Practices.”
The study protocol called for four groups of animals, two of which would be studied for 6 weeks to look at the acute effects of Lung ARS and the potential efficacy of AEOL 10150 as a countermeasure, and two which would be studied for six months to look at the chronic effects of Lung ARS and the potential efficacy of AEOL 10150 as a countermeasure. Twenty animals received a 40 mg loading dose of AEOL 10150 two hours after exposure and then received 20 mg of AEOL 10150 three times per week for four weeks. This approach has the added benefit of not requiring biodosimetry (a means of laboratory analysis of the blood to determine the level of radiation exposure).
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