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The symptoms, which can include sudden onset of fever, rash, headache and stiff neck, can progress rapidly.
Because invasive meningococcal disease can progress so rapidly, high levels of circulating antibodies are critical for protection. Epidemiology and Prevention of Vaccine-Preventable Diseases (The Pink Book: Course Textbook).05) survival advantage, statistically significant differences in body weights and wet lung weights were seen over the first six weeks of the study. The FDA has a special “Animal Rule” under which compounds may be approved for use against chemical and nuclear threats on the strength of animal efficacy studies, which allows the potential for an accelerated approval path versus conventional pharmaceutical applications.
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The symptoms, which can include sudden onset of fever, rash, headache and stiff neck, can progress rapidly.
Five serogroups cause the majority of meningococcal disease worldwide: A, B, C, W-135 and Y[1]. Novartis is the only company with leading positions in these areas.
References [1.
Data to Be Presented at the 55th Annual Meeting of the Radiation Research Society in October
MISSION VIEJO, Calif.05) survival advantage, statistically significant differences in body weights and wet lung weights were seen over the first six weeks of the study.
AEOL 10150 offers several unique advantages as a countermeasure for the treatment of ARS, mustard gas and chlorine gas for civilian and military populations.
-- Commercial Application – Additionally, AEOL 10150 is being developed for use as an adjunct to cancer radiation therapy, and animal data suggest that the compound protects healthy normal cells from the effects of radiation without compromising the efficacy of the radiation in killing tumor cells. A compound with the potential to protect against multiple threats would be of significant benefit in both the military and civilian efforts to protect citizens against potential threats. Studies funded by the National Institutes for Health are currently underway evaluating AEOL 10150 as a treatment for exposure to mustard gas and will shortly be initiated to evaluate the compound as a treatment for exposure to chlorine gas.
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